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. Author manuscript; available in PMC: 2014 Aug 7.
Published in final edited form as: Cell Mol Bioeng. 2014 Jan 1;7(1):73–85. doi: 10.1007/s12195-013-0318-3

Table 1.

Parameters used in mathematical model

Parameter* Description Value Notes or Sources
Nsarc Number of sarcomeres 8 -
Nnodes Number of nodes 9 Nnodes = Nsarc + 1
Lsarc Length of sarcomere 1.6 ± 0.063 μm (mean ± standard error) Randomly generated using a normal distribution [17]
t0 Start time 0 seconds [17]
tf End time 600 seconds [17]
td Time step 10 seconds [17]
ksarc Sarcomere stiffness 33.1 nN/μm [25]
m Sarcomere mass 8.25 μg [19]
γ Dampening parameter of internal viscoelasticity 0.01 nN-s/μm Calibration exercise
η Dampening parameter of cytoplasmic drag 6.5 nN-s/μm Calibration exercise
fc Maximal myosin contractile force (i.e., maximal fcontract) 32.7 nN Calibration exercise
a Amplitude of fluctuation function, y(t) 0 < a ≤ 1 Randomly generated using a uniform distribution
T Period of fluctuation function, y(t) 10 ± 10% minutes for myosin.
4 ± 10% minutes for actin.		 Randomly generated using a normal distribution
ϕ Phase shift of fluctuation function, y(t) − π ≤ ϕ ≤ π Randomly generated using a uniform distribution
*

: Unless otherwise mentioned in the text, all the parameters remain constant throughout all simulations, with the exception of Lsarc, which is generated from a normal distribution.