Figure 3. Ingestion of BAF or MPA through the sugar or blood meal results in reduced DENV titers.
BAF (50 µM) or MPA (250 µM) was mixed with 10% sucrose (A–B) or an infectious blood (C–D) and fed to mosquitoes. A) DENV titers at 7 dpbm of mosquitoes given BAF in a sugar meal were decreased when compared to the control group, but the difference was not significant (p = 0.0553). B) DENV titers at 7 dpbm of mosquitoes given MPA in a sugar meal were significantly reduced. C) Ingestion of BAF with an infectious blood meal reduced the DENV titers significantly. D) Ingestion of MPA with an infectious blood meal also reduced the titers significantly. (A–D) The red bar indicates a median value of titers. *; p<0.05, Mann-Whitney test. Descriptive statistics for DENV infection assays are presented in supplementary table S2.