Figure 6. Identification and comparison of differentially expressed E₂ responsive genes in the monkey and bovine CL.

Venn diagrams representing the number of differentially expressed E₂ responsive genes identified in monkey (M) and bovine (B) microarray data available from the GEO database. Data analyzed by Bioconductor analysis tool employing ≥1 fold change cut-off and statistical filters with Benjamini and Hochberg correction factor for false discovery rate. The circles designated for each time point post PGF_2α is represented as orange (24 h, M), blue (3 h, B), red (6 h, B) and green (18 h, B). A comparison of total number of differentially expressed up and down regulated E₂ responsive genes found common between 24 h, M vs. 3 h, B (A); 24 h, M vs. 6 h, B (B) and 24 h, M vs. 18 h, B (C) post PGF_2α treatment are presented.