Table 2. Results of the evolutionary conservation analyses using the ConSurf server.
Conservation score | ||||
dbSNP | Amino acid change | SWISS-PROT | UniProt | UniRef90 |
rs200555543 | F499C | 6 | 5 | 5 |
rs147547282 | Y275C | 5 | 5 | 4 |
rs146655862 | V129M | 9 | 9 | 9 |
rs72554626 | T498A | 7 | 8 | 8 |
rs5317 | F487V | 7 | 9 | 9 |
rs5315 | V403E | 9 | 9 | 8 |
A conservation score between 1–4 is considered variable; 5–6 is intermediate; 7–9 is conserved.