Figure 5. The secretions of HSP90α, HA, and PGE₂ into cell culture medium were increased by compressive loading.

Fibroblasts were seeded to collagen sponge and incubated for 24(A: HSP90α, B: HA, C: PGE₂) was measured by ELISA. A value of concentration was normalized by WST-1 value. The results are represented as the mean ± SEM (error bars) of five experiments. Statistical analysis was performed using the Dunnett’s multiple test between non-loaded group and each of loaded group, and statistical significance was taken as p<0.05. A value of p was expressed as: *; p<0.05, **; p<0.01, and ***; p<0.001.