Table 3. Multivariable linear regression model of predictors of CD4 count, stratified by gender (n = 5379).
Female (n = 3302) | Male (n = 2077) | |||||
Parameter | β | 95% CI | p-value | β | 95% CI | p-value |
Time on ART | ||||||
0 to 1 year (per year of ART up to 1 year) | 109.8 | 92.5 to 127.0 | <0.001 | 65.6 | 45.2 to 86.0 | <0.001 |
>1 year (per year of ART after 1 year) | 38.4 | 32.1 to 44.7 | <0.001 | 22.6 | 16.9 to 28.4 | <0.001 |
Age | 0.1 | −0.8 to 1.0 | 0.777 | 0.3 | −0.6 to 1.1 | 0.578 |
TB co-infection | −104.4 | −161.3 to −47.4 | <0.001 | −109.5 | −159.0 to −60.1 | <0.001 |
Pregnant | −31.8 | −53.1 to −10.7 | 0.003 | n/a | n/a | n/a |
Deworming | −67.3 | −103.9 to −30.7 | <0.001 | −34.3 | −88.7 to 20.1 | 0.217 |
Deworming×Time on ART interaction† | ||||||
Deworming during 0 to 1 year on ART | 63.0 | 6.0 to 120.1 | 0.030 | 13.0 | −57.4 to 83.4 | 0.717 |
Deworming during >1 year on ART | −15.4 | −32.6 to 1.8 | 0.078 | −6.9 | −29.3 to 15.5 | 0.544 |
Predicted difference in CD4 count between patients receiving versus not receiving deworming therapy in the past 90 days. The interaction terms were separated by duration of prior ART use as up to 1 year of therapy versus greater than 1 year of therapy.