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. 2014 Aug 7;9(8):e102843. doi: 10.1371/journal.pone.0102843

Figure 7. Identification of beta-cell markers in islets from diabetic NOD mice compared to STZ-induced diabetic Balb/c mice.

Figure 7

Representative pancreas sections from 4/c mice without or with STZ-induced diabetes were immunostained for glucagon (red) and Glut-2, PDX-1, Ngn3, PC-1/3 and GLP-1 (green, as indicated). Sections are counterstained with DAPI to visualize nuclei (and infiltrating immune cells). The insert on the glucagon and PC-1/3 panel indicates double-positive cells in an area where all glucagon cells are positive for PC-1. Scale bar = 10 µm.