Synthetic growth defects in cells that lack Set1 complex function in addition to partial NIMA function. (A) Representative images of cells of the indicated genotypes carrying H1-chRFP and GFP-Tub grown at the semipermissive temperature for nimA7 (35°) and fixed for microscopic analysis. (B) Categorization of cells of different genotypes based on the number of nuclei. Orange bars represent cells containing one or abnormal numbers of nuclei. WT, n = 65; nimA7, n = 72; ΔAn-swd1, n = 70; and nimA7 + ΔAn-swd1, n = 79. Strains: WT = HA365, nimA7 = MG153, ΔAn-swd1 = MG160, and nimA7 + ΔAn-swd1 = MG159.