Cells lacking Set1 complex function and carrying the nimA7ts allele have enhanced mitotic defects. Absence of An-swd1 or An-set1 confers dependence on the SAC in nimA7 cells but not in nimT23 cells at the permissive temperature (32°) as seen by the colony growth of strains of the indicated genotypes after 96 hr. Strains: WT = R153, nimA7 = CDS790, ΔAn-swd1 = MG218, nimA7 + ΔAn-swd1 = MG215, ΔAn-mad2 = CDS629, ΔAn-swd1 + ΔAn-mad2 = MG383, nimA7 + ΔAn-mad2 = MG381, nimT23 + ΔAn-mad2 = MG405, nimA7 + ΔAn-swd1 + ΔAn-mad2 = MG384, nimT23 + ΔAn-swd1 = MG219, nimT23 = SO53, and nimT23 + ΔAn-swd1 + ΔAn-mad2 = MG402.