Figure 5.

LD curve under constant population size. Simulated values of r² and ${\widehat{\sigma }}_{\text{d}}^2$ were generated using MACS (Chen et al. 2009). ${\sigma }_{\text{d}}^2$ was calculated using the method of Hill (1975), ρ was calculated from Equation 4, and $\stackrel{\sim }{\rho }$ from Equation 5. All calculations assume that 2N = 1000, u = 1.48 × 10⁻⁸, and c = 10⁻⁸ per nucleotide. Simulations involve 10⁹ bp of DNA, which are sequenced in a sample of 100 homologous chromosomes.