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. 2013 Nov 14;56(24):9982–10002. doi: 10.1021/jm401251p

Figure 5.

Figure 5

11a protects against CIA. Disease is shown by each of mean arthritis score ((A) PBS, n = 13; 11a, n = 13, data pooled from two independent experiments), hind paw width ((B) n = 7, data from a single experiment), and incidence (C,D) indicated by the % of mice developing a severity score ≥2 ((C) cumulative incidence) or ≥4 ((D) high score incidence). Results are expressed as mean scores ± SEM for PBS or 11a-treatment groups of mice exposed to collagen. The numbers of each of total (E), CD4+ (F), CD8+ (G), and γδ (H) T cells in DLN of individual mice from the naïve (n = 7), PBS-treated (n = 13) and 11a-treated (n = 13) groups are shown. For statistical analysis, *p < 0.05 and **p < 0.01.