Table 4.
Topological Distribution of Holins in TCDB According to Family
| TC # | Family Name |
Predicted Topologies: |
Likely Topology |
||
|---|---|---|---|---|---|
| HMMTOP | MEMSAT | SPOCTOPUS | |||
| 1.E.1 | P21 Holin S Famiy | 1 – 2 | 1 | 1 | 1 |
| 1.E.2 | λ Holin S Family | 1 – 3 | 1 – 3 | 0 – 3 | 2 – 3 |
| 1.E.3 | P2 Holin TM (P2 Holin) Family | 2 – 3 | 2 – 3 | 3 | 3 |
| 1.E.4 | LydA Holin (LydA Holin) Famil | 2 – 3 | 1 – 2 | 2 | 2 – 3 |
| 1.E.5 | PRD1 Phage P35 Holin (P35 Holin) Family | 2 – 3 | 1 – 3 | 1 – 3 | 3 |
| 1.E.6 | T7 Holin (T7 Holin) Family | 1 – 2 | 1 | 1 | 1 |
| 1.E.7 | HP1 Holin (HP1 Holin) Famil | 1 | 1 | 1 | 1 |
| 1.E.8 | T4 Holin (T4 Holin) Family | 1 – 2 | 1 | 1 | 1 |
| 1.E.9 | T4 Immunity (T4 Imm) Family | 1 – 3 | 1 – 2 | 1 – 3 | 2 |
| 1.E.10 | Bacillus subtilis φ29 Holin (φ29 Holin) Family | 2 – 3 | 3 | 3 | 3 |
| 1.E.11 | φ11 Holin (φ11 Holin) Family | 1 – 2 | 1 – 2 | 1 – 2 | 2 |
| 1.E.12 | φAdh Holin (φAdh Holin) Family | 0 – 1 | 1 | 0 – 1 | 1 |
| 1.E.13 | Firmicute phage φU53 Holin (φU53 Holin) Family | 3 | 2 | 3 | 2 |
| 1.E.14 | LrgA Holin (LrgA Holin) Family | 3 – 4 | 3 – 4 | 4 | 4 |
| 1.E.15 | ArpQ Holin (ArpQ Holin) Family | 2 | 2 | 2 | 2 |
| 1.E.16 | Cph1 Holin (Cph1 Holin) Family | 3 | 2 – 3 | 2 – 3 | 3 |
| 1.E.17 | BlyA Holin (BlyA Holin) Family | 1 | 1 | 1 | 1 |
| 1.E.18 | Lactococcus lactis Phage r1t Holin (r1t Holin) Family | 0 – 2 | 1 – 2 | 1 – 2 | 2 |
| 1.E.19 | Clostridium difficile TcdE Holin (TcdE Holin) Family | 1 – 4 | 3 – 4 | 2 – 4 | 4 |
| 1.E.20 | Pseudomonas aeruginosa Hol Holin (Hol Holin) Family | 3 | 1 – 2 | 1 – 2 | 1 – 2 |
| 1.E.21 | Listeria Phage A118 Holin (Hol118) Family | 3 | 2 – 3 | 2 – 3 | 3 |
| 1.E.22 | Neisserial Phage-associated Holin (NP-Holin) Family | 1 | 1 | 1 | 1 |
| 1.E.23 | Bacillus Spore Morphogenesis and Germination Holin (BSH) Family | 3 | 2 | 2 – 3 | 3 |
| 1.E.24 | Bacterophase Dp-1 Holin (Dp-1 Holin) Family | 2 | 1 – 2 | 1 – 2 | 2 |
| 1.E.25 | Pseudomonas phage F116 Holin (F116 Holin) Family | 1 – 2 | 1 – 2 | 1 – 2 | 2 |
| 1.E.26 | Holin LLH (Holin LLH) Family | 1 – 2 | 1 | 0 – 1 | 1 |
| 1.E.27 | BlhA Holin (BlhA Holin) Family | 1 | 1 | 1 | 1 |
| 1.E.28 | Streptomyces aureofaciens Phage Mu1/6 Holin (Mu1/6 Holin) Family | 2 | 1 – 2 | 0 – 2 | 2 |
| 1.E.29 | Holin Hol44 (Hol44) Family | 2 – 3 | 1 – 2 | 1 – 3 | 2 |
| 1.E.30 | Vibrio Holin (Vibrio Holin) Family | 1 | 1 | 0 | 1 |
| 1.E.31 | SPP1 Holin (SPP1 Holin) Family | 1 – 2 | 1 – 2 | 0 – 2 | 2 |
| 1.E.32 | Actinobacterial 1 TMS Holin (A-1 Holin) Family | 3 – 1 | 1 – 2 | 1 – 2 | 1 – 2 |
| 1.E.33 | 2 or 3 TMS Putative Holin (2/3 Holin) Family | 2 – 3 | 1 – 3 | 1 – 3 | 2 – 3 |
| 1.E.34 | Putative Actinobacterial Holin-X (Hol-X) Family | 2 | 2 | 2 | 2 |
| 1.E.35 | Mycobacterial 1 TMS Phage Holin (M1 Hol) Family | 0 – 1 | 1 | 0 | 1 |
| 1.E.36 | Mycobacterial 2 TMS Phage Holin (M2 Hol) Family | 1 – 5 | 1, 2, or 4 | 0 – 4 | 2 |
| 1.E.37 | Phage T1 Holin (T1 Holin) Family | 1 | 1 | 1 | 1 |
| 1.E.38 | Staphylococcus phage P68 Putative Holin (P68 Hol) Family | 2 | 2 | 1 | 2 |
| 1.E.39 | Mycobacterial Phage PBI1 Gp36 Holin (Gp36 Hol) Family | 2 | 2 | 2 | 2 |
| 1.E.40 | The Mycobacterial 4 TMS Phage Holin (MP4 Holin) Family | 4 | 2 – 4 | 2 – 5 | 4 |
| 1.E.41 | Deinococcus/Thermus Holin (D/T-Hol) Family | 3 | 2 | 3 | 3 |
| 1.E.42 | Putative Holin-like Toxin (Hol-Tox) Family | 1 | 1 | 1 | 1 |
| 1.E.43 | Putative Transglycosylase-associated Holin (T-A Hol) Family | 3 – 4 | 2 – 3 | 3 – 4 | 3 |
| 1.E.44 | The Putative Lactococcus lactis Holin (LLHol) Family | 1 – 2 | 1 – 2 | 1 – 2 | 1 – 2 |
| 1.E.45 | Xanthomonas Phage Holin (XanPHol) Family | 2 | 1 | 1 | 1 |
| 1.E.46 | Prophage Hp1 Holin (Hp1Hol) Family | 1 | 2 | 1 | 1 |
| 1.E.47 | Caulobacter Phage Holin (CauHol) Family | 2 | 2 | 2 | 2 |
| 1.E.48 | Enterobacterial Holin (EBHol) Family | 1 | 1 | 1 | 1 |
| 1.E.49 | Family Putative Treponema 4 TMS Holin (Tre4Hol) Family | 0, 1, or 4 | 1, 3, or 4 | 1, or 4 | 4 |
| 1.E.50 | Beta-Proteobacterial Holin (BP-Hol) Family | 1 | 1 | 1 | 1 |
| 1.E.51 | Putative Listeria Phage Holin (LP-Hol) Family | 1 | 1 | 1 – 2 | 1 |
| 1.E.52 | Flp/Fap Pilin Putative Holin (FFPP-Hol) Family | 1 – 2 | 1 | 1 | 1 |
| 1.E.53 | Toxic Hok/Gef Protein (Hok/Gef) Family | 0 – 1 | 1 – 2 | 1 | 1 |