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. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: Immunol Res. 2014 Aug;59(0):3–11. doi: 10.1007/s12026-014-8543-y

Fig. 2. Model for LBP/CD14/MD2-dependent transformation of E promoting TLR4 dependent cell activation by E.

Fig. 2

Potency of E is amplified by interactions with E-binding proteins that modify the presentation of E to TLR4. See text for additional details. Note that TLR4-expressing cells include those that express TLR4 ± MD-2.