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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: DNA Repair (Amst). 2014 Jun 30;21:78–86. doi: 10.1016/j.dnarep.2014.05.012

Figure 1. DNA alkylation repair contributes to longevity.

Figure 1

A) Survival curves of wild type (black lines, n=37), Aag−/− (red line, n=29), Mgmt−/− (blue line, n=50) and Aag−/− Mgmt−/− (purple line, n=31). Pair-wise comparisons: Aag−/− to wild type, p=0.1003; Mgmt−/− to wild type, p=0.4752; Aag−/− Mgmt−/− to wild type, p=0.04, all Log-rank (Mantel-Cox) test. B) Histopathological classification of pathologies found in WT (n=18), Aag−/− (n=24), Mgmt−/− (n=35), and Aag−/− Mgmt−/− (n=31) mice.