Figure 5. I-BET151 reduces onset and severity of EAE.
Mice were pretreated with 3 mg/kg I-BET151 for 3 days prior to immunization with MOG35–55 peptide and daily throughout the experiment. Clinical symptoms were scored daily and values shown are Means ± SEM. (n=4–5) *p<0.05, t-test. Data represent 1 out of 2 independent experiments