Table 2.

Treatments that have shown efficacy in the treatment of low bone mineral density in anorexia nervosa

Treatment	Effect on bone mineral density	Treatment duration	References
Physiologic estrogen replacement	2.6% increase in spine BMD	18 months	[25]
IGF-I + oral contraceptives	1.8% increase in spine BMD	9 months	[24]
DHEA + oral contraceptives	Maintenance of BMD as compared to loss of BMD in placebo group	18 months	[72]
Bisphosphonates	3–4% increase in spine BMD 2% increase in hip BMD	12 months	[29]
Teriparatide	6–10% increase in spine BMD	6 months	[111]