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The fold change in the mRNA expression for ALP, BSP, OCN, OPN and OSN in MC3T3-E1 cells relative to the control on days 3 (a) and 7 (b). The control was assigned an optical density reference value of 1.0 (*p < 0.05). BMP-2, bone morphogenetic protein-2; EMD, enamel matrix derivative; MTA, mineral trioxide aggregate; ALP, alkaline phosphatase; BSP, bone sialoprotein; OCN, osteocalcin; OPN, osteopontin; OSN, osteonectin.
