Table 4.
Effect of HAC loading on mainstream smoke yields of toxicants under HCI-VO smoking conditions
| Variable | Experimental cigarette | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| K715 | K712 | K721 | K731 | D711 1 | D712 | D721 | D732 | S712 | S713 | S721 | |
| Cigarette 2 | |||||||||||
| HAC loading (mg/cig) | 0 | 48 | 72 | 88 | 0 | 30 | 45 | 55 | 0 | 20.4 | 30.6 |
| Split gap (mm) | 0 | 10 | 16 | 20 | 0 | 10 | 16 | 20 | 0 | 10 | 16 |
| Circumference (mm) | 24.6 | 24.6 | 24.6 | 24.6 | 21.0 | 21.0 | 21.0 | 21.0 | 17.0 | 17.0 | 17.0 |
| Analyte | |||||||||||
| Ammonia (μg/cig) | 17.6* | 16.3* | 16.3* | 11.5 | 15.6 | 14.8* | 14.7* | 7.9 | 17.7 | 14.1 | 11.6 |
| Hydrogen cyanide (μg/cig) | 163.9 | 132.2* | ǂ108.0 | ǂ118.8* | 148.7 | 110.5 | 94.0 | 74.0 | 120.3* | 97.4 | 134.9* |
| Acetaldehyde (μg/cig) | 611.1 | 444.1 | 246.9* | 260.5* | 522.9 | 427.6 | 314.4* | 289.4* | 441.1 | 361.8* | 366.2* |
| Acetone (μg/cig) | 305.3 | 152.6 | 46.1* | 52.1* | 251.8 | 169.1 | 96.9* | 98.2* | 202.6 | 145. *8 | 128.3* |
| Acrolein (μg/cig) | 91.3 | 40.6 | 12.4* | 11.8* | 89.0 | 57.2 | 34.5* | 32.3* | 76.0 | 52.1 | 39.9 |
| Butyraldehyde (μg/cig) | 42.2 | 15.6 | 6.0* | 5.9* | 39.3 | 19.0 | 10.3* | 12.0* | 31.2 | 17.5 | 13.9 |
| Crotonaldehyde (μg/cig) | 25.8 | 3.7 | 0.8* | 0.7* | 22.5 | 7.7 | 3.2* | 4.4* | 20.5 | 7.9 | 5.6 |
| Formaldehyde (μg/cig) | 45.7 | 28.2 | 23.6* | 23.5* | 52.1 | 42.9* | ǂ36.7* | ǂ31.9 | 63.8 | 51.9 | 45.1 |
| Methyl ethyl ketone (μg/cig) | 73.9 | 21.4 | 5.9* | 6.5* | 66.4 | 31.0 | 15.2* | 17.0* | 49.6 | 26.4 | 21.3 |
| Propionaldehyde (μg/cig) | 55.7 | 32.5 | 11.7* | 13.3* | 51.0 | 35.9 | 22.9* | 20.9* | 39.1 | 30.3* | 28.5* |
| Pyridine (μg/cig) | 9.6 | 2.1 | 0.7* | 0.7* | 20.0 | 3.6 | 1.2* | 1.3* | 11.1 | 3.7 | 2.1 |
| Quinoline (μg/cig) | 0.2 | 0.3 | 0.3* | 0.3* | 0.6 | 0.4* | 0.3 | 0.4* | 0.2 | 0.3 | 0.2 |
| Styrene (μg/cig) | 11.7 | 1.5 | 0.4* | 0.5* | 12.8 | 2.0 | 0.5 | 0.4 | 9.0 | 1.8* | 1.0* |
| Nitric oxide (μg/cig) | 101.9 | 129.4 | 115.3 | 95.9 | 86.2 | 83.8* | 86.3* | 76.1 | ǂ74.4* | 78.1* | ǂ69.1 |
| 1,3-Butadiene (μg/cig) | 81.4* | 76.0* | ǂ29.9 | ǂ32.8 | 80.1 | 66.2 | 52.3 | 42.7 | 69.8* | 49.9 | 62.4* |
| Acrylonitrile (μg/cig) | 19.6 | 11.4 | 4.2* | 3.8* | 19.0 | 12.2 | 8.5 | 6.0 | 18.9 | 10.8* | 10.9* |
| Isoprene (μg/cig) | 812.1 | 572.2 | 148.6* | 165.6* | 779.4 | 518.3 | 361.3 | 251.3 | 731.0 | 451.9* | 500.2* |
| Benzene (μg/cig) | 68.5 | 29.6 | 6.9* | 6.6* | 60.6 | 27.1 | 16.4 | 10.6 | 42.9 | 19.2* | 19.6* |
| Toluene (μg/cig) | 98.8 | 23.5 | 6.3* | 4.8* | 84.0 | 24.0 | 13.4 | 9.4 | 54.6 | 17.1* | 16.4* |
| NFDPM (mg/cig) | 18.3* | ǂ17.2* | ǂ16.2 | ǂ16.5 | 15.8 | 15.5* | 15.1* | 14.4* | 13.1* | 13.3* | 13.8* |
| Nicotine (mg/cig) | 1.67* | 1.60* | ǂ1.43 | ǂ1.34 | 1.67 | ǂ1.63 | ǂ1.57 | 1.36 | ǂ1.33* | 1.4* | ǂ1.25 |
| CO (mg/cig) | 14.4* | ǂ13.6* | ǂ12.0 | 14.9* | 11.3 | 11.0* | 11.2* | 11.9* | 9.9* | 9.6* | 11.6 |
| Puff no. | 10.1 | 9.9 | 9.7 | 8.7 | 9.1 | 9.2* | 8.2 | 10.0* | 6.8 | 7.7 | 6.4 |
| NFDPM (mg/cig) | 7.2 | 8.9* | 8.4* | 8.6* | 7.2 | ǂ6.8* | 7.4* | ǂ6.2 | 5.8 | 6.5 | 7.8 |
| Nicotine (mg/cig) | 0.65 | 0.88* | ǂ0.78 | ǂ0.85* | 0.65 | ǂ0.71* | 0.75* | ǂ0.67 | 0.56* | 0.65* | 0.78 |
| CO (mg/cig) | 6.0* | 6.7* | 6.8* | 9.1 | 6.0 | 4.7* | 5.2* | 5.1* | 4.4* | 4.7* | 7.3 |
| Puff no. | 6.9 | 7.8 | 6.9 | 7.0 | 6.9 | 6.5 | 6.2 | 6.5 | 5.1 | 5.5 | 5.3 |
1Cigarette D711 used a triacetin plasticiser; all other cigarettes used tri-ethyl citrate.
2Split-gap sizes changed with cigarette design.
Lack of statistical difference at the 95% confidence level are denoted by * or ǂ.
Significance testing was not conducted for cigarette code D711 in comparison to D712, D721 or D732 as it‘s construction was slightly different to the other 21 mm cigarettes – it’s data are included for comparative purposes only. Significance testing was also not conducted on puff numbers as these are not discussed in the manuscript.