Figure 2.

Effects of Rg1 on CCl₄-induced hepatic fibrogenesis. Hepatic fibrosis was detected by Masson's trichromic staining. Representative photomicrographs of liver histology from each group are shown as follows: Control (A), CCl₄ alone (B), CCl₄+Bicyclol (C), CCl₄+Rg1-10 mg/kg (D), CCl₄+Rg1-20 mg/kg (E) and CCl₄+Rg1-40 mg/kg (F). Original magnification: ×40. Scale bar, 100 μm. The fibrosis score (G) was evaluated in ten randomly selected fields from each slide at a magnification of ×200. (H) The content of hydroxyproline in liver tissues. All data were expressed as means±SD of six animals. ^cP<0.01 vs control. ^fP<0.01 vs CCl₄ alone.