Figure 4.

Effects of Rg1 on the hepatic CYP2E1 mRNA levels and ADH activity in rats with ethanol exposure. Rats were treated with 6% (v/v) alcohol water for 8 weeks, and Rg1 and Bicyclol were administrated at the last two weeks (once a day). (A) The ethanol intake was record during the modeling period. (B) CYP2E1 mRNA levels were quantified with GAPDH as an internal control. Quantitative analysis was taken three independent qPCR analyses. (C) ADH activity in rat liver with ethanol exposure. n=6. Data are presented as mean±SD.