Figure 1.

Effect of ALDH2 knockout on survival status post-alcohol consumption in mice. (A) Four week survival curves of mice during ethanol consumption at final concentration (18%). The mice of the two water drinking groups and WT mice treated with alcohol all survived, but half (n=7) of the KO alcohol mice died at the end of experiment. (B, C, and D) BW, HW, and AW were all decreased in the KO alcohol mice compared with the WT alcohol mice. n=7 for each group. Mean±SEM. ^bP<0.05 vs WT. ^eP<0.05 vs WT+Alcohol. ^hP<0.05 vs KO.