Table 2. Test of reference compounds in anti-HCV assays.
| Compound | CC50 (nmol/L) | IC50 (nmol/L) |
||
|---|---|---|---|---|
| HCV infection assay | HCV replicon assay | NS3/4A-Seap | ||
| VX-950 | >10000 | 528±103 | 613±96 | 931±153 |
| BMS-790052 | >1000 | 0.054±0.010 | 0.078±0.015 | 1000 |
| Mycophenolic acid | >10000 | 520±29 | 468±103 | >10000 |
| Ribavirin | >100000 | >100000 | >100000 | >100000 |