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. 2014 Aug 8;8:273. doi: 10.3389/fnbeh.2014.00273

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Copyright © 2014 Cominski, Jiao, Catuzzi, Stewart and Pang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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LTP of the dentate gyrus field EPSP (fEPSP) following HFS of the medial perforant pathway in SD and WKY rats. SD rats exhibited early and late phase LTP of the fEPSP (A). In contrast, WKY rats did not demonstrate LTP at either early or late time points (B). Displayed are input–output (i/o) curves showing the baseline response, early phase LTP and late phase LTP. Shown are an average of two i/o curves generated prior to HFS (baseline), an average of i/o curves generated 15-min and 1-h after HFS (early), and an average of i/o curves generated 2- and 3-h after HFS (late).