Table 1. Previous case-control studies on miR-27a (rs895819), miR-146a (rs2910164), miR-196a-2 (rs11614913), miR-492 (rs2289030) and miR-608 (rs4919510) SNPs and colorectal cancer risk.

SNP	Study	Controls, n	CRC, n	Population	Effect of SNP
miR-27a T>C	Hezova R et al. 2012 [31]	212	197	Caucasian	No association
rs895819
miR-146a G>C	Lv M et al. 2013 [26]	540	353	Asian	CC genotype↓
rs2910164	Hezova R et al. 2012 [31]	212	197	Caucasian	No association
	Min KT et al. 2012 [27]	502	446	Asian	No association
	Ma L et al. 2013 [35]	1203	1147	Asian	GC/CC genotypes↓
	Parlayan C et al. 2014 [37]	524	116	Asian	No association
	Hu X et al. 2014 [36]	373	276	Asian	CG genotype↓
	Vinci S et al. 2013 [32]	178	160	Caucasian	No association
miR-196a-2 C>T	Lv M et al. 2013 [26]	540	353	Asian	T allele↑
rs11614913	Zhan JF et al. 2011 [29]	543	252	Asian	C allele↑
	Chen H et al. 2012 [30]	407	126	Asian	No association
	Hezova R et al. 2012 [31]	212	197	Caucasian	No association
	Min KT et al. 2012 [27]	502	446	Asian	CC genotype↑
	Zhu L et al. 2012 [28]	588	573	Asian	CC/CT genotype↑
	Vinci S et al. 2013 [32]	178	160	Caucasian	No association
miR-492 G>C	No studies
rs2289030
miR-608 C>G	Ryan et al. 2012 [42]	245	446	African-American/Caucasian	No association
rs4919510

SNP – single nucleotide polymorphism;

CRC – colorectal cancer;

↑- increased risk;

↓- decreased risk.