Table 1. Features of fast-spiking inhibitory interneurons and gamma oscillations.
Unique feature | References |
---|---|
A | |
Basket cell network | 93, 94, 95, 96, 97 |
Perisomatic control of pyramidal cells | 56, 86, 89, 103, 104 |
Fast-spiking (up to >100 Hz) | 48, 56, 86, 88, 108 |
Rapid AP kinetics and high Na+ entry ratio | 134, 135, 138, 139, 141 |
High numbers of mitochondria | 74, 118, 119, 121, 123 |
Generation of gamma oscillations | 22, 36, 49, 51, 52 |
B | |
Strong relationship to higher brain functions | 25, 26, 28, 30, 31, 33 |
High energy utilization | 41, 57, 63, 64, 67 |
Exquisite sensitivity to metabolic stress | 41, 44, 47, 163, 164 |
AP, action potential.
Some unique features of (A) fast-spiking, parvalbumin-positive interneurons and (B) gamma oscillations (30 to 100 Hz) are summarized, including a selection of key references. Note that mitochondria in parvalbumin-positive interneurons also contain higher levels of cytochrome c oxidase (complex IV) and cytochrome c.