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. 2014 Jun 4;34(8):1270–1282. doi: 10.1038/jcbfm.2014.104

Table 1. Features of fast-spiking inhibitory interneurons and gamma oscillations.

Unique feature References
A
 Basket cell network 93, 94, 95, 96, 97
 Perisomatic control of pyramidal cells 56, 86, 89, 103, 104
 Fast-spiking (up to >100 Hz) 48, 56, 86, 88, 108
 Rapid AP kinetics and high Na+ entry ratio 134, 135, 138, 139, 141
 High numbers of mitochondria 74, 118, 119, 121, 123
 Generation of gamma oscillations 22, 36, 49, 51, 52
   
B
 Strong relationship to higher brain functions 25, 26, 28, 30, 31, 33
 High energy utilization 41, 57, 63, 64, 67
 Exquisite sensitivity to metabolic stress 41, 44, 47, 163, 164

AP, action potential.

Some unique features of (A) fast-spiking, parvalbumin-positive interneurons and (B) gamma oscillations (30 to 100 Hz) are summarized, including a selection of key references. Note that mitochondria in parvalbumin-positive interneurons also contain higher levels of cytochrome c oxidase (complex IV) and cytochrome c.