Table 2A. Bivariate analysis—Influence of DAT genotype on binding potential.
| DAT genotype |
CSF corrected SRTM2 CFT: TBI |
CSF corrected SRTM2 CFT: control |
||||
|---|---|---|---|---|---|---|
|
9-carriers (N=6) |
10/10 (N=5) |
9-carriers (N=5) |
10/10 (N=8) |
|||
| Mean BP±s.e.m. | Mean BP±s.e.m. | P-value | Mean BP±s.e.m. | Mean BP±s.e.m. | P-value | |
| Caudate | 2.877±0.324 | 4.777±0.521 | 0.011 | 5.429±0.139 | 4.826±0.222 | 0.073 |
| Putamen | 2.760±0.203 | 3.674±0.173 | 0.009 | 4.966±0.319 | 4.478±0.182 | 0.178 |
| Striatum | 2.884±0.272 | 3.449±0.342 | 0.229 | 3.922±0.367 | 3.916±0.320 | 0.991 |
| DRD2 genotype |
A1-carriers (N=7) |
A2/A2 (N=5) |
A1-carriers (N=6) |
A2/A2 (N=7) |
||
|---|---|---|---|---|---|---|
| Mean BP±s.e.m. | Mean BP±s.e.m. | P-value | Mean BP±s.e.m. | Mean BP±s.e.m. | P-value | |
| Caudate | 4.249±0.541 | 2.850±0.311 | 0.101 | 4.956±0.307 | 5.145±0.118 | 0.591 |
| Putamen | 3.471±0.222 | 2.657±0.172 | 0.034 | 4.610±0.256 | 4.713±0.250 | 0.779 |
| Striatum | 3.233±0.334 | 2.980±0.243 | 0.614 | 4.491±0.291 | 3.428±0.231 | 0.014 |
BP, binding potential; CSF, cerebrospinal fluid; DAT, dopamine transporter; DRD2, D2 receptor gene; TBI, traumatic brain injury.
Bold entries are made for P-values representing comparisons that are statistically significant.