LLLT significantly improves neurobehavioral performance in KO animals. A time course of NSS (A) and fold changes of body weight (B) after mTBI and LLLT. The NSS and relative body weight changes were measured and expressed as Figures 1B and 1C with nine mice in each group. *P<0.05, **P<0.01, and ***P<0.001 compared in the presence versus absence of LLLT in KO mice. KO, knockout; LLLT, low-level laser therapy; mTBI, mild traumatic brain injury; NSS, neurologic severity score; WT, wild-type.