Figure 3.

(A) Representative in vivo microscopy images of mouse pial arterioles and their response to inhalation of 10% CO₂ 3 hours after sham surgery (upper panels) or SAH (lower panels). For each animal, the left and right panels show the same vessel. (B) Quantification of experiments shown above. Vessel diameter in the sham-operated animals increased immediately upon ventilation with 10% CO₂. In contrast, the diameter of cerebral arterioles of mice subjected to SAH showed no change in response to elevated PaCO₂. SAH, subarachnoid hemorrhage; SEM, standard error of the mean. *P<0.001 versus baseline; n=6 mice per group.