Figure 5.
In vivo electrophysiology was used to find the spikes generated per second from wide dynamic range neurons during and immediately following different types of stimuli. Average spikes per second in bortezomib rat cells were compared against those for naïve rats for each stimulus type, and afterdischarges in bortezomib rat cells were compared against afterdischarges for naïve rats for each stimulus type. Representative analog recordings data for naïve and bortezomib-treated rat neurons are pictured at the top of the figure with the horizontal lines indicating the type and duration of stimuli during each recording. The bar graphs at the bottom summarize the grouped data.