Table 2.
Comparison of Embryo Quality Between Abnormal Methylation and Normal Methylation.a
| Day 3 Embryo Quality | Abnormal Methylation | Normal Methylation |
|---|---|---|
| Cell number | 4.5 ± 1.6 | 5.0 ± 2.4b |
| Percentage of grade (%) | ||
| Grade 1 | 17.4 (4/23) | 25.6 (44/172)b |
| Grade 2 | 34.8 (8/23) | 20.3 (35/172)b |
| Grade 3 | 26.1 (6/23) | 37.8 (65/172)b |
| Grade 4 | 21.7 (5/23) | 16.3 (28/172)b |
| Arrested embryos (%)c | 21.7 (5/23) | 14.5 (25/172)b |
Abbreviation: DMR, differentially methylated regions
aAbnormal methylation of the 3 DMRs were found in 23 embryos, while normal methylation in 172 embryos.
bNo significant difference (P > .05; chi-square test was used).
cThe embryos stopped developing from day 2 to day 3.