Table 4.
Cartilage damage index stratified by baseline Kellgren-Lawrence (KL) grade
| Cartilage measure | KL = 0 (n = 4) mean (SD) | KL = 1 (n = 19) mean (SD) | KL = 2 (n = 40) mean (SD) | KL = 3 (n = 34) mean (SD) | KL = 4 (n = 5) mean (SD) | p-value for trend |
|---|---|---|---|---|---|---|
| |
Cross-sectional |
|||||
|
Femur CDI (Baseline) |
771.99 (157.40) |
750.75 (159.50) |
781.47 (114.73) |
634.00 (218.90) |
583.92 (434.01) |
<0.01 |
|
Tibia CDI (Baseline) |
363.07 (103.74) |
314.96 (60.46) |
343.96 (66.72) |
272.83 (94.26) |
199.81 (163.56) |
<0.01 |
|
Tibiofemoral CDI (Baseline) |
1135.1 (257.41) |
1065.7 (207.06) |
1125.4 (155.11) |
906.83 (304.59) |
783.73 (595.54) |
<0.01 |
| |
Longitudinal |
|||||
|
Femur CDI (Change) |
−81.06 (46.06) |
−30.35 (43.25) |
−36.72 (59.38) |
−72.92 (62.13) |
−109.4 (159.37) |
0.02 |
|
Tibia CDI (Change) |
−56.37 (43.48) |
−17.85 (32.13) |
−15.14 (26.74) |
−35.36 (49.33) |
−30.86 (33.75) |
0.40 |
| Tibiofemoral CDI (Change) | −137.40 (80.56) | −48.19 (61.81) | −51.86 (69.27) | −108.30 (90.93) | −140.20 (190.81) | 0.03 |
Notes: change = follow-up minus baseline; SD = standard deviation.