Figure 5.
Antitumor activity of various treatments against BEL-7402 tumors. (A) tumor growth curves for mice treated with saline plus NIR laser (n=6), HAuNS-TSL plus NIR laser (n=6), DOX-TSL alone (n=6), and DOX&HAuNS-TSL plus NIR laser (n=6). All mice were injected for total three times, and all tumors in mice, except the group of DOX-TSL, were irradiated by NIR laser (2.0 W/cm2 for 5 minutes) for total three times at 24h after each injection. (B) Photographs of tumors and (C) average tumor weights in different treatment groups. Tumors were removed on day 22 for all groups except the saline plus laser group, in which tumors were removed on day 12. (D) Representative photographs of tumors in DOX&HAuNS-TSL plus NIR laser and HAuNS-TSL plus NIR laser before and after the treatment.