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. 2014 Apr 8;2:6. doi: 10.3389/fbioe.2014.00006

Table 1.

Material properties for bone used for the remodeling simulation from Mullender and Huiskes (1995), Hernandez et al. (2001), Komarova et al. (2003), Hambli et al. (2009).

Parameters Notation Trabecular bone Cortical bone
GENERAL PARAMETERS
Initial elastic modulus E0 (MPa) 2000 17000
Poisson ratio ν 0.3 0.3
Initial density ρ (g/cm3) 0.764 1.4
Density coefficient C (g/cm3) 4000 80003
Density exponent P 3 3.
Ash exponent Q 2.74 2.74
DAMAGE LAW PARAMETERS
Fatigue parameter γ 0.2 0.2
Fatigue exponent β 0.4 0.4
MINERALIZATION PARAMETERS
Initial ash fraction α0 0.6 0.6
Maximum physiological value αmax 0.7 0.7
Velocity of the mineralization k (days−1) 0.0003387 0.0003387
STIMULUS PARAMETERS
Mechanosensitivity of the osteocyte μk (nmol mm J−1 h−1) 0.5 0.5
Osteocytes density Noc (mm−3) 10625 10625
Spatial influence factor d0 (μm) 0.1 0.1
Accommodation velocity parameter λ (days−1) 0.002 0.002
Initial setpoint value Sk0(Jm3) 0.0025 0.0025
BMU PARAMETERS
Osteoclasts
Osteoblasts
Notation Trabecular Cortical Notation Trabecular Cortical

α1 (osteoclasts/day) 3 3 α2 (osteoblasts/day) 4 4
β1 (osteoclasts/day) 0.2 0.2 β2 (osteoblasts/day) 0.0017 0.0017
k1 (osteoclasts/day) 0.24 0.024 k2 (osteoblasts/day) 0.02 0.002
A1 1.6 1.6 A1 −1.6 −1.6
B1 −0.49 −0.49 B2 0.6 0.6
γ1 (g/J) 16.67 16.67 γ2 (g/J) 33.37 33.37
xC (t = 0) (osteoclasts) 15 15 xB (t = 0) (osteoblasts) 1 1