Table 6.
Demographic and biochemical features of subjects with and without rs10865710* variation
| GG | GC + CC | P-value | |
|---|---|---|---|
| n | 107 | 761 | NA |
| Gender(M/F) | 27 / 80 | 194 / 567 | 0.954 |
| Body height(cm) | 158.14 ± 8.33 | 156.46 ± 8.03 | 0.033 |
| Body weight(kg) | 57.58 ± 11.73 | 55.84 ± 10. 52 | 0.134 |
| BMI(kg/m2) | 22.92 ± 3.54 | 22.73 ± 3.43 | 0.633 |
| SBP(mmHg) | 126.85 ± 21.05 | 127.60 ± 21.03 | 0.678 |
| DBP(mmHg) † | 80.00(75.00 – 86.00) | 80.00(70.00 – 88.00) | 0.398 |
| Waist(cm) | 79.26 ± 11.34 | 77.57 ± 10.29 | 0.178 |
| Hip(cm) | 93.41 ± 7.64 | 92.05 ± 7.42 | 0.095 |
| WHR | 0.85 ± 0.09 | 0.84 ± 0.08 | 0.735 |
| FPG(mmol/L) | 5.57 ± 1.29 | 5.38 ± 1. 84 | 0.026 |
| TG(mmol/L) | 1.57 ± 1.56 | 1.49 ± 1. 27 | 0.643 |
| HDLc(mmol/L) | 1.54 ± 0.46 | 1.60 ± 0. 77 | 0.396 |
| LDLc(mmol/L) | 2.57 ± 0.91 | 2.67 ± 0.90 | 0.201 |
| TC(mmol/L) | 5.41 ± 1.09 | 5.50 ± 1.11 | 0.471 |
| ALT(mmol/L) | 24.16 ± 25.15 | 21.30 ± 16.97 | 0.388 |
| AST(mmol/L) | 29.00 ± 15.85 | 28.03 ± 10.91 | 0.751 |
| GGT(U/L) | 29.95 ± 22.16 | 26.14 ± 19.17 | 0.079 |
| ALP(U/L) | 76.17 ± 24.69 | 77.88 ± 26.05 | 0.602 |
| FINS(mlU/L) † | 6.04(3.89 – 9.54) | 5.68(3.71 – 8.79) | 0.306 |
| HOMA-IR † | 1.44(0.93 – 2.45) | 1.42(0.86 – 2.28) | 0.592 |
| HSCRP(mg/L) † | 1.00(1.00 – 2.40) | 1.00(1.00 – 2.30) | 0.475 |
| MS(+/−) | 25 / 82 (23.4%) | 130 / 631 (17.1%) | 0.112 |
ALP, alkaline phosphatase ; ALT, alanine transaminase; AST, aspartate transaminase; BMI, body mass index; DBP, diastolic blood pressure; FPG, fasting plasma glucose; FINS, fasting insulin; GGT, gamma-glutamyl transpeptidase; HDLc, high-density lipoprotein cholesterol; HOMA-IR, homoeostatic metabolic assessment insulin resistance index; HSCRP, high sensitive C-reactive protein; LDLc, low-density lipoprotein cholesterol; MS, metabolic syndrome; NA, not analyzed; NAFLD, non-alcoholic fatty liver disease; SBP, systolic blood pressure; TC, total cholesterol; TG, triglyceride; WHR, waist-to-hip ratio.
†
Continuous data with skewed distribution
*
rs10865710=C-681G