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. 2014 Aug 8;9(8):e103845. doi: 10.1371/journal.pone.0103845

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© 2014 Santos et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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These panels represent the 12 solutions - one for each of the predicted dynamics - which best predict the experimental ratio between total actin and total moesin as measured by Barrero-Villar et al. 2009 [10] (black solid circles). REC_ratio: receptor ratio inside the cap; FILAMIN _ratio: filamin-A ratio inside the cap; MOESIN _ratio+ACTIN _ratio: ratio of moesin within the cap over the total amount of actin and moesin, plus ratio of actin within the cap over the total amount of actin and moesin; ACTIN _ratio: proportion of actin in the cap; MOESIN _ratio: proportion of moesin in the cap; COFILIN_i: inactive cofilin ratio with respect to the total amount of cofilin; COFILIN_a: proportion of active cofilin over the total amount of cofilin; HIV: virus units per lymphocyte. The HIV variable correlates with the intensity of the signal inside the lymphocyte triggered by the virus.