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. 2014 Aug 8;9(8):e103905. doi: 10.1371/journal.pone.0103905

Table 4. Sensitivities, specificities, positive and negative predictive values and kappa analysis.

Fever patients ABI-extracted DNA (n = 865)
Sensitivity % (95% CI) Specificity % (95% CI) PPV % (95% CI) NPV % (95% CI) Kappa value
Pan-LAMP 91.5 (84.8–95.8) 100 (99.5–100) 100 (96.6–100) 98.7 (97.6–99.4) 0.95
Pf-LAMP 86.3 (78.7–92.0) 100 (99.5–100) 100 (96.4–100) 97.9 (96.6–98.8) 0.92

P.f.* = P. falciparum mono infections (n = 33), P.m.** = P.malariae mono infections (n = 13), P.f.*** P. falciparum mono and mixed.

infections (n = 41), CI = confidence interval, PPV = positive predictive value, NPV = negative predictive value.

Sensitivities, specificities, positive and negative predictive values and kappa analysis for detection of malaria DNA from fever patients and asymptomatic individuals with Pan and Pf-LAMP versus gold standard (real- time PCR corrected Cytochrome b nested PCR).