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. 2014 Aug 8;9(8):e104494. doi: 10.1371/journal.pone.0104494

Table 1. Summary of smoking adjustment factors (SAF) and the population attributable fraction (PAF) due to smoking for the major causes of deaths to the lungs.

Causes of death OR (95% CI for ever Population Smoking adjustment factors (SAF)d
smokersa attributable fraction Never smokers Ever smokers
Lung cancer 4.99 (4.00–6.22) 0.672 3.05 0.61
Chronic obstructive pulmonary diseases 3.68 (2.58–5.26) 0.579 2.37 0.65
Silicosisb 1.80 (1.20–2.60) 0.294 1.42 0.78
Pulmonary heart diseasec 1.78 (1.36–2.33) 0.286 1.40 0.79
Pulmonary tuberculosis 2.54 (1.24–5.22) 0.441 1.79 0.70

Abbreviations: OR, odds ratio (ever smoking vs. never smokers); 95% CI, 95% confidence interval.

a

All the odds ratios other than silicosis for smoking (ever vs. never smoking) was obtained from a case-control study of all adult deaths in Hong Kong [17].

b

We assumed Hong Kong male smokers having the same risk of silicosis as those of Italy ceramic workers; however, we had to use the incidence OR for silicosis (smoking vs. never smoking) to represent the mortality OR, as we do not have relevant mortality data in Hong Kong [18].

c

The odds ratio of other vascular disease was used to estimate the SAF-corrected SMR for pulmonary heart disease [17].

d

The SAF for smoking silicotics was numerically equal to 1/[(1-PAR%)RR] and that for nonsmoking silicotics was 1/(1-PAR%) (detailed calculations were illustrated in Supplement S1).