Figure 1. Lead Exposure Timeline.
Dams were exposed 2 weeks prior to mating and throughout pregnancy. Pups continued exposure post-natally during lactation and via direct exposure in drinking water until weaning at day 22. After discontinuation of Pb exposure, mice were assayed for physiological parameters at 3, 6, and 9 months of age at the Michigan Nutrition Obesity Research Center (MNORC), and sacrificed at 10 months of age.