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. 2014 Aug 8;9(8):e103918. doi: 10.1371/journal.pone.0103918

Table 4. Multivariate analysis of progression-free and overall survival.

Characteristic PFS OS
HR 95% CI p HR 95% CI p
CTCs at baseline ≥1 vs 0 3.0 1.53–6.13 .002 3.0 1.48–6.02 .002
Relapse/recurrent disease Local vs Distant 2.7 1.45–4.98 .002 2.3 1.14–4.80 .019
Argiris prognostic factors1 ≥3 vs 0–2 - - - 1.3 .60–2.89 .427
1

Argiris factors were included in the overall survival model only. Abbreviations: PFS, progression-free survival; OS, overall survival; HR, hazard ratio; CI, confidence intervals; CTCs, circulating tumor cells.