Table 1. Demographic data, duration of hospitalization and laboratory parameters of BSI cases.
| Community-acquiredBSI (n = 192) | Healthcare-associatedBSI (n = 85) | Community-onset BSI(n = 277) | Hospital-acquired BSI(n = 395) | p-value (ifsignificant) | |
| Age (years) * | 70 (IQR 60–81) | 71(IQR 63–78) | 70(IQR 61–80) | 64(IQR 52–72) | p<0.001 |
| Sex (f/m) | 93/99 | 44/41 | 137/140 | 144/151 | |
| BMI | 26.27(IQR 23.55–29.30;n = 136) | 25.22(IQR 22.31–28.08;n = 79) | 25.82(IQR 22.83–28.55;n = 215) | 25.02(22.11–28.91;n = 352) | |
| WBC (G/L) | 11.94(IQR 8.23–16.9) | 12.01(IQR 7.52–19.04) | 11.96(IQR 8.15–17.46) | 8.3(IQR 4.73–14.2;n = 127) | p<0.001 |
| NLCR | 0.88(IQR 0.81–0.92) | 0.89(IQR 0.8–0.93) | 0.88(IQR 0.81–0.92) | 0.85(IQR 0.78–0.91;n = 86) | p = 0.036 |
| C-reactive protein(mg/L) | 141.5(IQR 51–242) | 123.4(IQR 52.5–239.6;n = 84) | 133.9(IQR 51.6–240;n = 276) | 92.2(IQR 45.5–171.7;n = 388) | p<0.001 |
| Procalcitonin(ng/mL) | 1.27(IQR 0.39–8.28;n = 172) | 3.92(IQR 0.66–19.46;n = 76) | 1.62(IQR 0.42–12.03;n = 248) | 0.89(IQR 0.27–5.19;n = 361) | p = 0.001 |
| Interleukin-6(pg/mL) | 493.8(IQR 154.9–2055;n = 155) | 399.8(IQR 149.9–1188;n = 72) | 442.3(IQR 153–1776;n = 227) | 148(59.7–487.9;n = 332) | p<0.001 |
| Serum creatinine(mg/dL) | 1.32(IQR 1.01–2.06;n = 190) | 1.74(IQR 1.16–3.18;n = 82) | 1.36(IQR 1.03–2.42;n = 272) | 1.24(IQR 0.84–2.33;n = 357) | p = 0.008 |
| Days hospitalizedafter collection ofpositive bloodculture (days) | 10 (IQR 3–16) | 9 (IQR 6–15) | 10 (IQR 5–16) | 13 (IQR 8–23) | p<0.001 |
| 30-day mortality | 16/192 (8%) | 15/85 (18%) | 31/277 (11%) | 82/395 (21%) | p = 0.001 |
| 90-day mortality | 18/192 (9%) | 17/85 (20%) | 35/277 (13%) | 106/395 (27%) | p<0.001 |
* = Data available from all included patients unless otherwise stated.
Abbreviations: BMI, Body-mass index; BSI, blood stream infection; f, female; m, male; NLCR, neutrophyl leucocyte ratio; WBC, white blood cell count.