Figure 2.

Concentration-response curves for acetylcholine (ACh: 10^-9 – 10 ^-4 M) in isolated superior mesenteric artery rings, with intact endothelium and pre-contracted with L-phenylephrine (1 μM). The rings were obtained from rats of the groups control (C), diabetic sedentary (DS) and diabetic trained (DT). Data are expressed as mean ± standard error of the mean. The statistical differences were determined by two-way analysis of variance followed by Bonferroni post-test. ^** p < 0.01 and ^*** p < 0.001 vs. C; ^## p < 0.01 vs. DS.