Table 2.

Synthesis of Trisubstituted Oxazolidines.

Entry	R1	R2	Oxazolidine	Yield (%)
1	i-Pr	OMe	(2S, 4S)-3a	59
2	i-Pr	OEt	(2S, 4S)-3b	75
3	i-Pr	OBn	(2S, 4S)-3c	63
4	i-Pr	OPh	(2S, 4S)-3d	22
5	i-Pr	Me	(2S, 4S)-3e	53
6	i-Pr	Ph	(2S, 4S)-3f	55
7	i-Pr	m,p-Cl2C6H3	(2S, 4S)-3g	28
8	i-Pr	m,p-(CH3O)2C6H3	(2S, 4S)-3h	58
9	i-Pr	p-FC6H4	(2S, 4S)-3i	63
10	i-Pr	1-naphthyl	(2S, 4S)-3j	70
11	i-Pr	2-thienyl	(2S, 4S)-3k	37
12	Me	OMe	(2S, 4S)-4a	68
13	Me	OEt	(2S, 4S)-4b	68
14	Me	OBn	(2S, 4S)-4c	64
15	Me	OPh	(2S, 4S)-4d	14
16	Me	Me	(2S, 4S)-4e	68
17	Me	Ph	(2S, 4S)-4f	57
18	Me	m,p-Cl2C6H3	(2S, 4S)-4g	41
19	Me	m,p-(CH3O)2C6H3	(2S, 4S)-4h	90
20	Me	p-FC6H4	(2S, 4S)-4i	27
21	Me	1-naphthyl	(2S, 4S)-4j	33
22	Me	2-thienyl	(2S, 4S)-4k	25
23	Bn	OMe	(2S, 4S)-5a	66
24	Bn	OEt	(2S, 4S)-5b	81
25	Bn	OBn	(2S, 4S)-5c	76
26	Bn	OPh	(2S, 4S)-5d	5
27	Bn	Me	(2S, 4S)-5e	45
28	Bn	Ph	(2S, 4S)-5f	71
29	Bn	m,p-Cl2C6H3	(2S, 4S)-5g	30
30	Bn	m,p-(CH3O)2C6H3	(2S, 4S)-5h	98
31	Bn	p-FC6H4	(2S, 4S)-5i	51
32	Bn	1-naphthyl	(2S, 4S)-5j	96
33	Bn	2-thienyl	(2S, 4S)-5k	41
34	CH2OH	OMe	(±)-6a	38
35	CH2OH	OEt	(±)-6b	50
36	CH2OH	OBn	(±)-6c	37
37	CH2OH	OPh	(±)-6d	8
38	CH2OH	Me	(±)-6e	29
39	CH2OH	Ph	(±)-6f	23
40	CH2OH	m,p-Cl2C6H3	(±)-6g	12
41	CH2OH	m,p-(CH3O)2C6H3	(±)-6h	38
42	CH2OH	p-FC6H4	(±)-6i	23
43	CH2OH	1-naphthyl	(±)-6j	24
44	CH2OH	2-thienyl	(±)-6k	58