Table 1.
Complication (reference) | Evidence of BKV infection or disease (reference) |
---|---|
Dysuria, hematuria, urgency/frequency, flank pain, bladder spasms (51)Obstructive nephropathy (46) | BKV urine PCR + |
| |
Renal tubulointerstitial disease (47, 48, 50, 53, 54) | IHC and/or EM + |
BK viruria | |
BK viremia in 4 patients (48, 50, 53) | |
| |
Encephalitis (44, 45, 49) | BKV CSF PCR + |
BKV PCR brain tissue + (49) | |
No histopathology (44, 45) | |
No brain tissue staining | |
| |
Pneumonia (43, 55) | SV40 lung tissue stain + |
viral intranuclear inclusions (43) | |
lung tissue cell culture BKV + (55) | |
lung tissue BKV PCR + (55) | |
| |
Pneumonitis (52) | BAL fluid with cells resembling decoy cells |
IHC + |
BKV, BK virus; ICH, immunohistochemistry; EM, electron micrograph; CSF, cerebrospinal fluid; PCR, polymerase chain reaction; BAL, bronchoalveolar lavage.