Table 3.
Hemorrhagic cystitis (HC) and and BK viruria in adult hematopoietic stem cell transplantation
| Study First author (reference) | Year | Study type | Type(s) of Transplant | Overall N | BK viruria | HC & BK viruriaa (%) | HC & aGVHDb | Outcome (death) |
|---|---|---|---|---|---|---|---|---|
| Bedi (6) | 1995 | Prospective | Autologous & Allogeneic | 147 | 50 | 20 (40%) | 13 (30%)c | N/A |
| Leung (68) | 2001 | Prospective | Autologous & Allogeneic | 50 | 50 | 20 (40%) | 4 (44%) | N/A |
| Asano (65) | 2003 | Retrospective | Allogeneic | 141 | N/A | 10 | 13 (100%) | 9 |
| Yamamoto (70) | 2003 | Retrospective | Allogeneic | 256 | N/A | 2 | 13 (72%) | 3 |
| Giraud (66) | 2006 | Prospective | Allogeneic | 90 | 30 | 13 (43%) | 6 (25%) | N/A |
| Giraud (67) | 2008 | Prospective | Allogeneic | 175 | 83 | 23 (28%) | 12 (22%) | N/A |
| Silva (69) | 2010 | Prospective | Allogeneic | 209 | 96 | 25 (26%) | 8 (12%) | N/A |
a
% BK viruric patients who developed HC.
b
Grade II–IV acute GVHD (aGVHD) unless otherwise specified.
c
Grades of aGVHD not given.
N/A, not available; HC, hemorrhagic cystitis; aGVHD, acute graft-versus host disease.