Table 2. Multivariable logistic regression analysis of predictors of AI treatment discontinuation, including individual symptoms.

Multivariable logistic regression resulting from step-down analysis of treatment discontinuation during the first year of AI therapy due to baseline sleep and concentration difficulties before AI initiation and patient characteristics (n=428, area under the curve = 0.65)

Variable	Odds Ratio (95% CI)	p-value
Age	0.97 (0.95–1.00)	0.028
Drug (exemestane vs. letrozole)	1.63 (1.07–2.49)	0.024
Sleep quality (PSQI >5 vs. ≤5)	1.79 (1.15–2.79)	0.010
Concentration (vs. none)		0.017
Not at all or slight	0.75 (0.42–1.33)
Moderate-extreme	2.62 (1.22–5.65)