Extended Data Table 1.

Best-fit parameters for viral dynamics pre-ART and during ART.

Fitted parameters include v₀, the effective infectious viral load from which the infection starts, a, the growth rate of viral load during acute infection, and d, the decay rate of viral load once treatment is started. See the Methods section, including Equations 1 and 2, for detailed descriptions.

Fitted parameters				Derived parameters
Days until ART started	log10(v0)	a	d	Half-life (In(2)/d)	R0	log10(AUC)
3	-	-	-	-	-	2.6
3	-	-	-	-	-	2.6
3	-	-	-	-	-	2.6
3	-	-	-	-	-	2.6
7	−1.16	2.19	0.50	1.38	17.10	5.1
7	1.44	1.45	0.29	2.37	14.57	5.7
7	−1.77	2.66	0.58	1.19	20.30	5.9
7	1.34	1.49	0.56	1.24	9.13	5.7
10	1.27	1.38	0.63	1.11	7.65	7.1
10	2.16	1.25	0.91	0.76	5.33	7.5
10	−0.25	1.55	0.51	1.36	10.32	6.3
10	−0.24	1.57	0.60	1.15	9.23	6.4
14	1.76	0.94	0.62	1.12	4.86	7.5
14	1.79	1.05	0.49	1.42	6.45	8.2
14	2.30	0.94	0.53	1.30	5.36	8.0
14	1.54	1.11	0.91	0.76	4.69	8.3
Mean	0.85	1.46	0.60	1.26	9.58	NA
STD	1.35	0.51	0.17	0.41	5.16	NA