Extended Data Table 2.
Best-fit parameters for viral dynamics following ART discontinuation.
Fitted parameters include vr, the infectious residual viral load from which the infection starts, r, the growth rate of viral load during rebound, and vmax, the viral setpoint reached after rebound. See the Methods section, including Equation 3, for detailed descriptions.
Fitted parameters | Derived Quantities | ||||
---|---|---|---|---|---|
| |||||
Days until ART started | log10(vr) | r | log10(vmax) | R0 | Estimated days to VL=50 copies/ml |
3 | −6.57 | 1.12 | 4.22 | 6.10 | 17.0 |
3 | −0.27 | 0.27 | 4.83 | 1.84 | 16.8 |
3 | −2.18 | 0.85 | 4.88 | 4.51 | 10.5 |
3 | −4.34 | 0.80 | 5.22 | 4.20 | 17.5 |
7 | 0.72 | 0.40 | 4.70 | 2.53 | 5.6 |
7 | −1.23 | 0.94 | 3.62 | 8.12 | 7.2 |
7 | 0.76 | 0.49 | 3.79 | 2.75 | 4.4 |
7 | −0.60 | 0.69 | 5.01 | 3.78 | 7.7 |
10 | −1.33 | 0.96 | 5.26 | 4.95 | 7.3 |
10 | −1.17 | 0.89 | 4.00 | 3.74 | 7.4 |
10 | 1.25 | 0.24 | 5.71 | 1.84 | 4.2 |
10 | 0.12 | 0.38 | 2.50 | 2.24 | 10.1 |
14 | 1.38 | 0.19 | 3.39 | 1.56 | 3.9 |
14 | 1.23 | 0.36 | 4.22 | 2.34 | 3.0 |
14 | 1.07 | 0.52 | 4.41 | 3.02 | 2.7 |
14 | 0.24 | 0.51 | 5.00 | 2.37 | 6.6 |