Table 2.
Distribution of characteristics of the overall population and never smokers
| All | Never smokers | |||||
|---|---|---|---|---|---|---|
| Cases, n (%) | Controls, n (%) | P-value1 | Cases, n (%) | Controls, n (%) | P-value1 | |
| Total | 12,688 | 14,452 | 2,504 | 7,276 | ||
| Study | ||||||
| FHS | 979 (7.72) | 1,173 (8.12) | <0.0001 | 377 (15.06) | 678 (9.32) | <0.0001 |
| UCLA | 609 (4.80) | 1,038 (7.18) | 109 (4.35) | 470 (6.46) | ||
| WELD | 571 (4.50) | 571 (3.95) | 52 (2.08) | 279 (3.83) | ||
| NELCS | 276 (2.18) | 251 (1.74) | 11 (0.44) | 95 (1.31) | ||
| SLRI | 439 (3.46) | 928 (6.42) | 152 (6.07) | 455 (6.25) | ||
| Harvard | 2,119 (16.70) | 1,517 (10.50) | 135 (5.39) | 479 (6.58) | ||
| Mayo | 4,192 (33.04) | 2,235 (15.46) | 635 (25.36) | 812 (11.16) | ||
| Moffitt | 117 (0.92) | 384 (2.66) | 39 (1.56) | 303 (4.16) | ||
| GenAir | 74 (0.58) | 702 (4.86) | 47 (1.88) | 466 (6.40) | ||
| CREST | 401 (3.16) | 551 (3.81) | 45 (1.80) | 237 (3.26) | ||
| Liverpool | 286 (2.25) | 888 (6.14) | 17 (0.68) | 247 (3.39) | ||
| IARC | 255 (2.01) | 1,012 (7.00) | 198 (7.91) | 831 (11.42) | ||
| Hawaii | 628 (4.95) | 587 (4.06) | 45 (1.80) | 224 (3.08) | ||
| Kyushu | 190 (1.50) | 108 (0.75) | 59 (2.36) | 57 (0.78) | ||
| GEL-S 1 | 261 (2.06) | 674 (4.66) | 149 (5.95) | 585 (8.04) | ||
| GEL-S 2 | 367 (2.89) | 748 (5.18) | 228 (9.11) | 642 (8.82) | ||
| Aichi | 453 (3.57) | 815 (5.64) | 117 (4.67) | 319 (4.38) | ||
| Seoul | 471 (3.71) | 270 (1.87) | 89 (3.55) | 97 (1.33) | ||
| Region | ||||||
| North America | 9,930 (78.26) | 8,684 (60.09) | <0.0001 | 1,555 (62.10) | 3,795 (52.16) | <0.0001 |
| Europe | 1,016 (8.01) | 3,153 (21.81) | 307 (12.26) | 1,781 (24.48) | ||
| Asia/Oceania | 1,742 (13.73) | 2,615 (18.09) | 642 (25.64) | 1,700 (23.36) | ||
| Age (years) | ||||||
| <45 | 1,021 (8.05) | 2,117 (14.65) | <0.0001 | 285 (11.38) | 1,154 (15.86) | <0.0001 |
| 45–49 | 898 (7.08) | 1,230 (8.51) | 209 (8.35) | 674 (9.26) | ||
| 50–54 | 1,096 (8.64) | 1,608 (11.13) | 255 (10.18) | 842 (11.57) | ||
| 55–59 | 1,609 (12.68) | 2,002 (13.85) | 300 (11.98) | 995 (13.68) | ||
| 60–64 | 1,763 (13.90) | 1,949 (13.49) | 306 (12.22) | 900 (12.37) | ||
| 65–69 | 2,181 (17.19) | 2,035 (14.08) | 387 (15.46) | 1,003 (13.79) | ||
| >=70 | 4,120 (32.47) | 3,511 (24.29) | 762 (30.43) | 1,708 (23.47) | ||
| Sex | ||||||
| Men | 6,378 (50.27) | 6,587 (45.58) | <0.0001 | 597 (23.84) | 2,308 (31.72) | <0.0001 |
| Women | 6,310 (49.73) | 7,865 (54.42) | 1,907 (76.16) | 4,968 (68.28) | ||
| Ethnicity | ||||||
| Non-Hispanic White | 9,478 (74.70) | 10,168 (70.36) | <0.0001 | 1,543 (61.62) | 4,696 (64.54) | <0.0001 |
| Asian | 2,131 (16.80) | 3,066 (21.22) | 766 (30.59) | 1,954 (26.86) | ||
| Black/African-American | 540 (4.26) | 627 (4.34) | 100 (3.99) | 330 (4.54) | ||
| Hispanic/Latino | 114 (0.90) | 261 (1.81) | 44 (1.76) | 132 (1.81) | ||
| Native American | 218 (1.72) | 47 (0.33) | 25 (1.00) | 16 (0.22) | ||
| Other | 207 (1.63) | 283 (1.96) | 26 (1.04) | 148 (2.03) | ||
| Histology | ||||||
| Adenocarcinoma | 6,006 (47.34) | 1,555 (62.10) | ||||
| Squamous cell carcinoma | 2,599 (20.48) | 211 (8.43) | ||||
| Large cell | 653 (5.15) | 95 (3.79) | ||||
| Other non-small cell | 790 (6.23) | 91 (3.63) | ||||
| Small cell | 1,177 (9.28) | 79 (3.15) | ||||
| Other/mixed/missing | 1,463 (11.53) | 473 (18.89) | ||||
1
P-values are for X2-tests comparing cases and controls.