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. Author manuscript; available in PMC: 2015 Oct 15.
Published in final edited form as: Int J Cancer. 2014 Mar 25;135(8):1918–1930. doi: 10.1002/ijc.28835

Table 3.

Joint effects of active smoking and exposure to secondhand smoke on lung cancer risk

Active
smoking
Exposed to
secondhand
smoke
Cases Controls Unadjusted
OR (95% CI)
Adjusted
OR1 (95% CI)
  Never   Never 651 2,167 1.00 Reference 1.00 Reference
  Never   Ever 1,817 4,890 1.24 (1.12–1.37) 1.27 (1.14–1.42)
  Ever   Never 1,219 1,074 3.78 (3.35–4.26) 2.83 (2.48–3.22)
  Ever   Ever 8,827 5,921 4.96 (4.52–5.45) 4.79 (4.32–5.32)
Adjusted ratio of odds ratios1 (95% CI)
  Overall: 1.33 (1.15–1.54)
  Adenocarcinoma: 1.44 (1.20–1.72)
  Squamous cell carcinoma: 1.12 (0.78–1.59)
  Large cell lung cancer: 1.13 (0.64–2.01)
  Small cell lung cancer: 0.79 (0.42–1.50)
1

Odds ratios adjusted for age, sex, race/ethnicity, and study