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. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: Mol Cancer Ther. 2014 Jul 14;13(8):2116–2126. doi: 10.1158/1535-7163.MCT-13-0952

Table 2.

IC50 values

IC50 (µM)

TDP1 TDP2

Compound Structure REC WCE REC
NCGC00183674 graphic file with name nihms599332t1.jpg 12.1 ± 1.7 (n=4) 51, 59 (n=2) >111
JLT048 graphic file with name nihms599332t2.jpg 7.7 ± 1.8 (n=5) 115, 148 (n=2) 32 ±10 (n=3)